Imaging brain chemistry and function in neuropsychiatric disorders.

Iranian Brain Imaging Database: A Neuropsychiatric Database of Healthy Brain

Introduction: The Iranian Brain Imaging Database (IBID) was initiated in 2017, with 5 major goals: provide researchers easy access to a neuroimaging database, provide normative quantitative measures of the brain for clinical research purposes, study the aging profile of the brain, examine the association of brain structure and function, and join the ENIGMA consortium. Many prestigious databases...

Neuropsychological and Neuropsychiatric Deficits Following Traumatic Brain Injury: Common Patterns and Neuropathological Mechanisms

Traumatic Brain Injury (TBI) in all degrees of injury severity mainly induces deviant cognitive, emotional and behavioral alterations that lead to their respective disorders. This brief overview strives to define the variables that determine the risk of occurrence of these disorders and to describe the common patterns of these disorders and their relevant neuropathogenetic mechanism(s). In addi...

Synthesis and biological evaluation of 99mTc(CO)3-OH-PP-CS2 for brain receptor imaging

Introduction: 5-HT1A receptor is related with a variety of neuropsychiatric disorders. . In this study a phenolic analogue derived from DWAY [Desmethyl WAY-100635 (N-(2-(1-(4-(2-methoxyphenyl)piperazinyl)-ethyl))-N-(2-pyridinyl) cyclohexanecarboxamide)] is used to design the desired structure of 5-HT1A receptor imaging agents after labeling with [99mTc (CO) 3(H2O) 3] + cor...

Letter to Editor: Neuropsychiatric Consequences of Deep Brain Stimulation in Patients with Chronic Movement Disorders

Ferulic acid, a phenolic compound with therapeutic effects in neuropsychiatric disorders, stimulates the production of nerve growth factor and endocannabinoids in rat brain

Introduction: Ferulic acid, a phenolic phytochemical with neuroprotective, anti-inflammatory, and antioxidant properties, has shown promising antidepressant-like effects in behavioral studies; however, its mechanism(s) of action have not been fully understood. Based on the contribution of nerve growth factor (NGF) and endocannabinoid signaling (eCBs) to the emotional or antidepressant activ...

NEUROPSYCHIATRIC DISORDERS IN THE OLDEST MEDICAL TEXTBOOK IN PERSIAN WRITTEN AROUND 990 A.D.

Written around 990 A.D Hidayat-Motaallemin Fil Tibb (Students’ Guide in Medicine) is the oldest general medical Text known to have been written in modern Persian. Little is known of the author other than the fact that he was apparently a well experienced practicing physician by t he name of Abu Bakr Rabi'bin Ahmadal-Akhawaini from Bukhara who claimed to be a second generation student of R...